foxo4 dri senolytic 2023 2024 Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of and Senomorphic Therapies The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications foxo4 dri peptide senolytic mouse study 2023 2024 Molecular modelling of the FOXO4 TP53 interaction to design peptides for the elimination of senescent cancer cells FOXO4 DRI Peptide for Cellular Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway Full article: Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics
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