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Similarly, ICV pretreatment or peripheral post-treatment with the DEETGE-Cal-Tat peptide was also able to decrease Keap1-Nrf2 interaction in the rat hippocampal CA1 region after global cerebral ischemia (GCI) and, as a consequence, to induce Nrf2 target genes and a powerful neuroprotection of hippocampal-dependent cognitive function after GCI [302]

Rev Physiol Biochem Pharmacol

Glutathione A powerful antioxidant peptide that plays a critical role in detoxifying the body, reducing oxidative stress, and supporting immune function