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First, each possible target for Rg1 could be determined by using the SwissTargetPrediction tool (Our study used SwissTargetPrediction ( Next, genes related to PD could be filtered using the GeneCards database ( These targets were then imported into Cytoscape 3.10 to establish a drug-target-disease network, followed by the construction of a protein-protein interaction (PPI) network using String database ( The PPI network was useful for the selection of targets for further analysis, representing areas with established experimental support

Within this review, we examine some of the studies by which zinc has exerted either neuroprotective or neurotoxic effects during global and focal cerebral ischemia

Absorbance was measured at 490 nm using a GloMax Discover Microplate Reader (Promega

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