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Cells 9:167 Jelinek T, Sevcikova T, Popkova T, Cerna L, Broskevicova L, Brozova L et al (2020) Limited efficacy of daratumumab in multiple myeloma with extramedullary disease

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Daily injections at the beginning are key for: Quickly fixing the deficiency Reducing severe symptoms Getting ready for ongoing treatment Secondary Phase: Weekly Injections for One Month After the first week, injections are given weekly for a month

As with all GLP-1 agonists, long-term post-marketing surveillance will be essential to characterize the pancreatic safety profile with greater statistical precision, particularly for rare events such as acute pancreatitis (estimated background rate of approximately 35 per 100,000 person-years in the general population) and the theoretical concern about pancreatic cancer