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Varenicline acts as a partial agonist of the 42 nicotinic acetylcholine receptor in the brain similar to nicotine, so it can reduce nicotine craving and withdrawal symptoms associated with nicotine dependence 5

Eligibility criteria stipulated that participants must be: Participant of the STOP program, Daily smoker trying to quit smoking Current alcohol user, as defined by reporting having consumed an alcoholic beverage in the past twelve months Alcohol consumption in the past twelve months - versus a more comprehensive alcohol use measure as the AUDIT-C was used to define current alcohol user in an effort to broaden the sample of participants amongst whom recruitment could take place

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and completed the 10-minute post-intervention (T3) self-administered questionnaire