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For example, fibroblast growth factor 21 is a new metabolic regulator that is produced mainly in the liver and participates in the regulation of lipid metabolism, including lipolysis, fatty acid oxidation and ketogenesis (Reference Coskun, Bina and Schneider37)

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Consistent with previously published reports, motif analysis of differentially AR bound peaks observed in response to HD (10 nM R1881), or common to both HD and LD treated VCAP or LNCAP cells, revealed AREs, FOXA1 and HoxB13 binding sequences as the top enriched motifs 40