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We additionally provide evidence that the inflammatory responses in general, and the changes in immune functions are modified by the lack of an accurate cholesterol metabolism

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The stimulus that usually activates macrophages to produce cytokines like IL-10 and TGF- is mainly IL-4, IL-13, and immunological complexes that suppress immune response, thus leading to tumor propagation ( HOTTIP (HOX Transcript Antisense Intergenic RNA) was found to correlate with M2 polarization of macrophages, particularly in endotoxin tolerance, a phenomenon of reduced response of macrophages to LPS ( MM2P lncRNA is an important regulator of the polarization of M2 macrophages