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Intermittent Fasting Intermittent fasting (IF) is a new dietary approach that involves scheduled periods of eating and fasting (calorie restriction), with complete or low-energy intake at regular intervals [355]

Therefore, the aim of this study is to address this gap by incorporating formal risk-of-bias assessment, to evaluate the relevance of PD using UPDRS minimal clinically important differences (MCIDs)

The underlying mechanisms for these effects are still far from clear but may include genetic factors and the anti-oxidant and anti-inflammatory properties of bilirubin

Furthermore, the study identified that subjects exhibiting normal serum vitamin B 12 levels in the presence of high erythrocyte folate were also more likely to develop cognitive impairment (Moore et al., 2014)