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Anti-inflammatory and antioxidant actions also contribute to its synergistic anticancer effects by dampening STAT3-driven tumor-promoting feedback and inhibiting oncogenic pathways including mTOR, PI3K/Akt, and Wnt/-catenin (Li et al., 2018

Our observed complex structure differs fundamentally from all previously published models of the hTrxR1hTrx1 complex and provides new insights into the catalytic mechanism of large, eukaryotic TrxRs

Strategies aimed at reducing high glucose levels by employing sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been shown to significantly lessen the onset of cellular senescence, potentially attributed to the synthesis of -hydroxybutyrate (Kulkarni et al., 2022)

Role of glucose metabolism in aggressive phenotype of fibroblast-like synoviocytes: latest evidence and therapeutic approaches in rheumatoid arthritis