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To further delineate pathways that are responsive to GSTO1 knockdown, we performed gene set enrichment analysis (GSEA) using the Bru-seq data (Supplementary Tables 12 and 13)

Subjects started at 2mg twice weekly and gradually increased the dosage until desired results were reached

This suggests heightened energy metabolism derived from amino acids, contrasting with weakened fat and sugar-derived energy metabolism in LN patients

MeOD) 171.8 (C, CO 2 tBu), 158.1 (C, FmocCO), 145.3 (C, Fmoc), 142.6 (C, Fmoc), 128.8 (CH, Fmoc), 128.2 (CH, Fmoc), 126.4 (CH, Fmoc), 121.0 (CH, Fmoc), 83.3 (C, C(CH 3 ) 3 ), 71.9 (CH, C-4), 68.2 (CH 2 , FmocCH 2 ), 62.9 (CH 2 , C-9), 56.5 (CH, C-1), 50.2 (CH, FmocCH), 40.8 (CH 2 , C-3), 37.3 (CH 2 , C-5), 35.5 (CH 2 , C-2), 33.6 (CH 2 , C-8), 28.3 (3CH 3 , C(CH 3 ) 3 ), 26.9 (CH 2 , C-7), 26.6 (CH 2 , C-6)